Detalhe da pesquisa
1.
Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders.
Altern Lab Anim
; 52(2): 117-131, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38235727
2.
Unraveling the mechanisms underlying drug-induced cholestatic liver injury: identifying key genes using machine learning techniques on human in vitro data sets.
Arch Toxicol
; 97(11): 2969-2981, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37603094
3.
ToxicoDB: an integrated database to mine and visualize large-scale toxicogenomic datasets.
Nucleic Acids Res
; 48(W1): W455-W462, 2020 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32421831
4.
Unravelling Mechanisms of Doxorubicin-Induced Toxicity in 3D Human Intestinal Organoids.
Int J Mol Sci
; 23(3)2022 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163210
5.
A Transcriptomic Approach to Elucidate the Mechanisms of Gefitinib-Induced Toxicity in Healthy Human Intestinal Organoids.
Int J Mol Sci
; 23(4)2022 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35216325
6.
Transcriptomic Analysis in Human 3D Skin Model Injected with Resorbable Hyaluronic Acid Fillers Reveals Foreign Body Response.
Int J Mol Sci
; 23(21)2022 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36361846
7.
Evaluation of Adverse Effects of Resorbable Hyaluronic Acid Fillers: Determination of Macrophage Responses.
Int J Mol Sci
; 23(13)2022 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35806280
8.
New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids.
Arch Toxicol
; 95(8): 2691-2718, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34151400
9.
High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability.
Arch Toxicol
; 93(10): 2895-2911, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31552476
10.
Transcriptomic and metabolomic data integration.
Brief Bioinform
; 17(5): 891-901, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26467821
11.
DTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds.
Arch Toxicol
; 91(6): 2343-2352, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28032149
12.
Xenobiotic metabolism in differentiated human bronchial epithelial cells.
Arch Toxicol
; 91(5): 2093-2105, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27738743
13.
Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop.
Regul Toxicol Pharmacol
; 91 Suppl 1: S3-S13, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28958911
14.
Pattern recognition methods to relate time profiles of gene expression with phenotypic data: a comparative study.
Bioinformatics
; 31(13): 2115-22, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25701576
15.
diXa: a data infrastructure for chemical safety assessment.
Bioinformatics
; 31(9): 1505-7, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25505093
16.
Integrative "-Omics" Analysis in Primary Human Hepatocytes Unravels Persistent Mechanisms of Cyclosporine A-Induced Cholestasis.
Chem Res Toxicol
; 29(12): 2164-2174, 2016 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27989131
17.
Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity.
Mutagenesis
; 31(5): 603-15, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27338304
18.
New insights into BaP-induced toxicity: role of major metabolites in transcriptomics and contribution to hepatocarcinogenesis.
Arch Toxicol
; 90(6): 1449-58, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26238291
19.
Distinct genotype-dependent differences in transcriptome responses in humans exposed to environmental carcinogens.
Carcinogenesis
; 36(10): 1154-61, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26233959
20.
Bayesian Network Inference Enables Unbiased Phenotypic Anchoring of Transcriptomic Responses to Cigarette Smoke in Humans.
Chem Res Toxicol
; 28(10): 1936-48, 2015 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26360787